Apoptotic gene expression in potentially fertile and subfertile men
نویسندگان
چکیده
منابع مشابه
Apoptotic gene expression in potentially fertile and subfertile men.
Human sperm contain similar amounts of protamine-1 (P1) and protamine-2 (P2). Although an aberrant protamine ratio have been observed in subfertile men, functional evidence is provided by protamine knockout mice exhibiting male infertility. As sperm DNA integrity is known to be linked with DNA fragmentation and apoptosis, we investigated whether the DNA fragmentation factor 40 (DFF40) ratio or ...
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Background: Phospholipids are distributed asymmetrically between inner and outer leaflets of the plasma membrane of live cells. Early during apoptosis, this asymmetry is disrupted and phosphatidylserine becomes exposed on the outside surface of the plasma membrane. There is little information about the effects of vitrification on apoptosis. Objective: The aim of the present study was to evaluat...
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Testicular biopsy specimens from 16 fertile and 10 subfertile men with normal male karyotype were studied quantitatively to provide histological and cytogenetic data for a basis of reference in assessing abnormalities of spermatogenesis. Histological studies included estimation of the proportion and activity of germinal epithelium and an assessment of tubular morphology. In cytogenetic preparat...
متن کاملvitrification induced apoptosis in spermatozoa from fertile and subfertile men
background: phospholipids are distributed asymmetrically between inner and outer leaflets of the plasma membrane of live cells. early during apoptosis, this asymmetry is disrupted and phosphatidylserine becomes exposed on the outside surface of the plasma membrane. there is little information about the effects of vitrification on apoptosis. objective: the aim of the present study was to evaluat...
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A receptive uterine environment is a key component in determining a successful reproductive outcome. We tested the hypothesis that endometrial gene expression patterns differ in fertile and subfertile dairy cow strains. Twelve lactating dairy cattle of strains characterized as having fertile (n = 6) and subfertile (n = 6) phenotypes underwent embryo transfer on day 7 of the reproductive cycle. ...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 2011
ISSN: 1360-9947,1460-2407
DOI: 10.1093/molehr/gar011